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A library of 363 glycoconjugates and C-nucleosides synthesized by our earlier reported methods were screened for their effect on isolated filarial glutamate cysteine ligase (GCL) and glutathione reductase (GR).
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The library has been tested against Leishmania donovani and Plasmodium falciparum, with activity at the micromolar level.
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Aptamers which specifically recognize targets are selected from random oligonucleotide library using systematic evolution of ligands by exponential enrichment (SELEX).
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Screening of Peptide Inhibitors of TACE from a Phage Display Random 15-Peptide Library by Recombinant TACE Ectodomain
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In the present study, a 15-peptide library was used to identify potential TACE antagonists.
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